Staphylococcal Coagulase: Mode of Action and Antigenicity
نویسندگان
چکیده
منابع مشابه
Staphylococcal coagulase; mode of action and antigenicity.
Different strains of staphylococci vary in ability to produce free coagulase. Methods are given for the selection of suitable strains and for the production and concentration of coagulase from one of them. Of animal plasmas examined, cow, sheep, dog, guinea-pig and mouse showed a relative deficiency in coagulase activator, while plasma of man, monkey, horse, cat, pig, fowl and rabbit contained ...
متن کاملPurification of staphylococcal coagulase.
Correlation between the pathogenicity of certain staphylococci and their ability to produce coagulase has led to extensive studies of the clotting enzyme. Walston (1935) precipitated the clotting substance from cell-free filtrates of appropriate staphylococcal cultures by the use of ethanol, acetic acid, or ammonium sulfate. Walker et al. (1948) partially purified staphylocoagulase by repeated ...
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OBJECTIVES Infections caused by Staphylococcus aureus might be treated with agents whose primary indications are for other infections. Clofazimine, an established anti-mycobacterial drug, could be such a candidate. However, the anti-staphylococcal properties of clofazimine have not been fully described and its mode of action, possibly involving inhibition of both RNA polymerase and a membrane-l...
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The plate test, a modification of the slide test described by Cadness-Graves was developed for the rapid identification of coagulase-positive staphylococci in conjunction with bacteriophage typing. An evaluation of 1,145 cultures by three coagulase-determination methods, the slide, tube, and plate tests, indicates that the plate test is as accurate as the slide tests, and the plate test agrees ...
متن کاملCoagulase-negative staphylococcal peritonitis: outcomes of cephalosporin-resistant strains.
Peritoneal dialysis (PD) peritonitis and subsequent relapses are undesirable complications for patients requiring home peritoneal dialysis. Coagulase-negative staphylococci (CoNS) remain a common cause of peritonitis. Strains of CoNS are emerging that are resistant to cephalosporins. It has been suggested that, if sensitivity testing shows resistance to cephalosporin but the patient is improvin...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1952
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-6-1-2-95